TGN-020
TGN-020 is a small molecule inhibitor of Aquaporin 4 (AQP4; IC50 = 3.1 μM), the predominant water channel in the central nervous system. It is a valuable research tool for studying water homeostasis, neuroinflammation, and edema in models of stroke, traumatic brain injury, and neuromyelitis optica spectrum disorders (NMOSD) in both in vitro and in vivo settings.
Product Specifications
CAS Number
51987-99-6
Product Name Alternative
Edema, AQP4, Aquaporin 4, Inhibitor, glial, inhibit, PROTAC Linker, PROTACLinker, PROTAC Linkers, TGN 020, TGN020, TGN-020, scar
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Aquaporin 4 blocker
Form
Powder
Solubility
Soluble in DMSO (up to 10 mg/ml with warming)
Smiles
O=C (Nc1nncs1) c1cccnc1
Molecular Formula
C8H6N4OS
Molecular Weight
206.22
Storage Conditions
RT
Notes
For research use only.
Other Product Names
N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide
Available Sizes
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