SRI-011381 hydrochloride
SRI-011381 hydrochloride is a novel small molecule agonist of the TGF-β signaling pathway. It is used in research for Alzheimer's disease, showing potential in both in vitro neuronal models and in vivo preclinical studies to modulate neuroprotective pathways.
Product Specifications
CAS Number
2070014-88-7
Product Name Alternative
Collagen-1, NALP3, neuroprotective, multiple, inhibit, Inhibitor, sclerosis, Smad, SRI 011381, SRI 011381 hydrochloride, SRI 011381 Hydrochloride, SRI011381, SRI-011381, SRI011381 Hydrochloride, SRI011381 hydrochloride, SRI-011381 Hydrochloride, SRI-011381 hydrochloride [1629138-41-5 (free base) ], α-SMA, Transforming growth factor beta, TGFbeta/Smad, TGF-beta/Smad, TGFbeta, TGF-beta, TGF-β/Smad, TGF-β, TGFβ, TGFb, TGF-b/Smad
Field of Research
Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
H2O:76.92 mg/mL (210.2 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.47 mM) ; DMSO:34.29 mg/mL (93.7 mM)
Smiles
Cl.O=C (NC1CCCCC1) N (CC1CCNCC1) Cc1ccccc1
Molecular Formula
C20H32ClN3O
Molecular Weight
365.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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