BMS-986142
BMS-986142 is a potent, selective, and reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM. It is a valuable research tool for studying BTK-dependent signaling in autoimmune and inflammatory disease models, both in cellular assays and in vivo studies.
Product Specifications
CAS Number
1643368-58-4
Product Name Alternative
BTK, Btk, BMS986142, BMS-986142, Bruton tyrosine kinase, BMS 986142, inhibit, Inhibitor
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.70% (May vary between batches)
Solubility
H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.49 mM) ; DMSO:45 mg/mL (78.59 mM)
Smiles
Cc1c (cccc1-n1c (=O) n (C) c2c (F) cccc2c1=O) -c1c (F) cc (C (N) =O) c2[nH]c3C[C@H] (CCc3c12) C (C) (C) O
Molecular Formula
C32H30F2N4O4
Molecular Weight
572.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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