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NAV-2729

NAV-2729 is a potent small molecule inhibitor targeting multiple ArfGEFs, including human ARNO, EFA6, BIG1, and BRAG2, as well as bacterial RalF proteins. It demonstrates particularly strong activity against BRAG2, Arf1, and Arf6. This tool compound is valuable for in vitro studies investigating Arf GTPase signaling pathways in cancer and infectious disease research.

Product Specifications

CAS Number

419547-11-8

Product Name Alternative

NAV2729, NAV-2729, NAV 2729, Inhibitor, inhibit, Arf1, Arf6

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Purity

98.83% (May vary between batches)

Solubility

DMSO:6.88 mg/mL (15.06 mM)

Smiles

[O-][N+] (=O) c1ccc (cc1) -c1cc (=O) n2nc (Cc3ccccc3) c (-c3ccc (Cl) cc3) c2[nH]1

Molecular Formula

C25H17ClN4O3

Molecular Weight

456.88

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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