NAV-2729
NAV-2729 is a potent small molecule inhibitor targeting multiple ArfGEFs, including human ARNO, EFA6, BIG1, and BRAG2, as well as bacterial RalF proteins. It demonstrates particularly strong activity against BRAG2, Arf1, and Arf6. This tool compound is valuable for in vitro studies investigating Arf GTPase signaling pathways in cancer and infectious disease research.
Product Specifications
CAS Number
419547-11-8
Product Name Alternative
NAV2729, NAV-2729, NAV 2729, Inhibitor, inhibit, Arf1, Arf6
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
98.83% (May vary between batches)
Solubility
DMSO:6.88 mg/mL (15.06 mM)
Smiles
[O-][N+] (=O) c1ccc (cc1) -c1cc (=O) n2nc (Cc3ccccc3) c (-c3ccc (Cl) cc3) c2[nH]1
Molecular Formula
C25H17ClN4O3
Molecular Weight
456.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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