MC-Val-Cit-PAB
MC-Val-Cit-PAB is a protease-cleavable linker utilized in the construction of antibody-drug conjugates (ADCs), such as the clinically approved brentuximab vedotin. It enables targeted drug delivery and release in both in vitro and in vivo research models for oncology and targeted therapy development.
Product Specifications
CAS Number
159857-80-4
Product Name Alternative
Inhibit, Inhibitor, MCValCitPAB, MC-Val-Cit-PAB, MC Val Cit PAB, Antibody-drug conjugates linkers, ADCLinker, ADC Linker, ADC Linkers
Field of Research
Neuroscience, Signal Transduction
Purity
98.03% (May vary between batches)
Solubility
DMSO:22 mg/mL (38.42 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.73 mM)
Smiles
[C@@H] (NC ([C@@H] (NC (CCCCCN1C (=O) C=CC1=O) =O) [C@H] (C) C) =O) (C (NC2=CC=C (CO) C=C2) =O) CCCNC (N) =O
Molecular Formula
C28H40N6O7
Molecular Weight
572.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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