Cabozantinib hydrochloride
Cabozantinib hydrochloride (XL184) is a multi-targeted tyrosine kinase inhibitor with potent activity against key receptors including VEGFR2, c-Met, Kit, Axl, and Flt4. It is widely used in preclinical research to investigate tumor angiogenesis, metastasis, and proliferation in both cellular assays and animal models of various cancers.
Product Specifications
CAS Number
1817759-42-4
Product Name Alternative
Cluster of differentiation antigen 135, CD135, CD117, c-Kit, cKit, c-Met/HGFR, cMet/HGFR, cMet, c-Met, antiangiogenic, Apoptosis, angiogenesis, B16F10 cells, Axl, Cabozantinib, Cabozantinib hydrochloride, Cabozantinib Hydrochloride, Cabozantinib hydrochloride (849217-68-1 (free base) ), BMS 907351, BMS907351, BMS-907351, A431, Inhibitor, inhibit, Mer, HGFR, Fms like tyrosine kinase 3, HT1080, FLT4, FLT3, Tyro3, VEGFR2/KDR, VEGFR, Vascular endothelial growth factor receptor, RORγ, RORα, TAMReceptor, TAM Receptor, SCFR, XL 184, XL184, XL-184
Field of Research
Cardiovascular Research, Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.09% (May vary between batches)
Solubility
DMSO:5.38 mg/mL (10 mM)
Smiles
Cl.COc1cc2nccc (Oc3ccc (NC (=O) C4 (CC4) C (=O) Nc4ccc (F) cc4) cc3) c2cc1OC
Molecular Formula
C28H25ClFN3O5
Molecular Weight
537.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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