Leniolisib
Leniolisib (CDZ173) is a selective PI3Kδ inhibitor with an IC50 of 11 nM. It is used in research to study immune dysregulation, including in vitro assays and in vivo models of diseases like activated phosphoinositide 3-kinase δ syndrome (APDS) .
Product Specifications
CAS Number
1354690-24-6
Product Name Alternative
Phosphoinositide 3-kinase, PI3Kδ, PI3K, CDZ 173, CDZ173, CDZ-173, DNA-PK, DNAPK, Inhibitor, Leniolisib, inhibit
Field of Research
Molecular Biology, Signal Transduction
Purity
99.88% (May vary between batches)
Solubility
H2O:Insoluble; Ethanol:10 mg/mL (22.2 mM) ; DMSO:16.67 mg/mL (37.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.44 mM)
Smiles
CCC (=O) N1CC[C@@H] (C1) Nc1ncnc2CCN (Cc12) c1cnc (OC) c (c1) C (F) (F) F
Molecular Formula
C21H25F3N6O2
Molecular Weight
450.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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