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Leniolisib

Leniolisib (CDZ173) is a selective PI3Kδ inhibitor with an IC50 of 11 nM. It is used in research to study immune dysregulation, including in vitro assays and in vivo models of diseases like activated phosphoinositide 3-kinase δ syndrome (APDS) .

Product Specifications

CAS Number

1354690-24-6

Product Name Alternative

Phosphoinositide 3-kinase, PI3Kδ, PI3K, CDZ 173, CDZ173, CDZ-173, DNA-PK, DNAPK, Inhibitor, Leniolisib, inhibit

Field of Research

Molecular Biology, Signal Transduction

Purity

99.88% (May vary between batches)

Solubility

H2O:Insoluble; Ethanol:10 mg/mL (22.2 mM) ; DMSO:16.67 mg/mL (37.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.44 mM)

Smiles

CCC (=O) N1CC[C@@H] (C1) Nc1ncnc2CCN (Cc12) c1cnc (OC) c (c1) C (F) (F) F

Molecular Formula

C21H25F3N6O2

Molecular Weight

450.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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