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SBI-0640756

SBI-756 is a novel, first-in-class small molecule inhibitor that selectively targets eIF4G1 to disrupt the eIF4F complex assembly. This mechanism has shown utility in preclinical cancer research, where it inhibits cap-dependent translation and demonstrates anti-proliferative effects in various in vitro cell-based assays.

Product Specifications

CAS Number

1821280-29-8

Product Name Alternative

Inhibit, Inhibitor, Eukaryotic Initiation Factor (eIF), eIF-4G, Autophagy, SBI 0640756, SBI0640756, SBI-0640756, SBI 756, SBI756, SBI-756

Field of Research

Cell Biology

Purity

99.75% (May vary between batches)

Solubility

H2O:Insoluble; DMSO:50 mg/mL (123.51 mM)

Smiles

Fc1cncc (\C=C\C (=O) c2c (-c3ccccc3) c3cc (Cl) ccc3[nH]c2=O) c1

Molecular Formula

C23H14ClFN2O2

Molecular Weight

404.82

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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