AZ876
AZ876 is a potent and selective liver X receptor (LXR) agonist, demonstrating high affinity for both human LXRα (Ki/EC50 = 7/6 nM) and LXRβ (Ki/EC50 = 11/73 nM) . This small molecule is a valuable research tool for studying LXR-mediated pathways in atherosclerosis, lipid metabolism, and inflammation in both cellular and animal models.
Product Specifications
CAS Number
898800-26-5
Product Name Alternative
AZ 876, AZ-876, AZ876, LXR, inhibit, Liver X Receptor, LiverXReceptor, Liver X receptor, Inhibitor
Field of Research
Metabolism Research
Purity
99.41% (May vary between batches)
Solubility
DMSO:55 mg/mL (125.12 mM) ;5% DMSO+40% PEG300+5% Tween 80+50% Saline:2.5 mg/mL (5.69 mM)
Smiles
CC (C) (C) N1C (=O) C (Nc2ccc (cc2) N2CCCCC2) =C (c2ccccc2) S1 (=O) =O
Molecular Formula
C24H29N3O3S
Molecular Weight
439.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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