AMZ30
AMZ30 is a potent and selective small molecule inhibitor of the methylesterase PME-1, exhibiting an IC50 of 600 nM. It effectively reduces levels of demethylated PP2A in cellular models, making it a valuable chemical probe for studying PP2A regulation in cancer and neurodegenerative disease research.
Product Specifications
CAS Number
1313613-09-0
Product Name Alternative
PME-1, inhibit, Inhibitor, AMZ 30, AMZ30, AMZ-30
Field of Research
Metabolism Research, Signal Transduction
Purity
98.81% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (48.76 mM)
Smiles
[O-][N+] (=O) c1cccc (c1) S (=O) (=O) n1cccc1\C=C (/C#N) S (=O) (=O) c1ccc (F) cc1
Molecular Formula
C19H12FN3O6S2
Molecular Weight
461.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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