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AMZ30

AMZ30 is a potent and selective small molecule inhibitor of the methylesterase PME-1, exhibiting an IC50 of 600 nM. It effectively reduces levels of demethylated PP2A in cellular models, making it a valuable chemical probe for studying PP2A regulation in cancer and neurodegenerative disease research.

Product Specifications

CAS Number

1313613-09-0

Product Name Alternative

PME-1, inhibit, Inhibitor, AMZ 30, AMZ30, AMZ-30

Field of Research

Metabolism Research, Signal Transduction

Purity

98.81% (May vary between batches)

Solubility

DMSO:22.5 mg/mL (48.76 mM)

Smiles

[O-][N+] (=O) c1cccc (c1) S (=O) (=O) n1cccc1\C=C (/C#N) S (=O) (=O) c1ccc (F) cc1

Molecular Formula

C19H12FN3O6S2

Molecular Weight

461.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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