AUT1
AUT1 is a novel and specific positive modulator of Kv3.1b and Kv3.2a potassium channels, exhibiting EC50 values of 4.7 μM and 4.9 μM, respectively. This small molecule is a valuable research tool for investigating Kv3 channel function in neuronal excitability, fast-spiking neurons, and potential therapeutic applications for neurological disorders in both in vitro and in vivo models.
Product Specifications
CAS Number
1311136-84-1
Product Name Alternative
AUT 1, AUT1, AUT-1, dysfunction, corticolimbic circuits, human recombinant, Inhibitor, KcsA, Kv3.1b, Kv3.1b channels, Kv3.2a, Kv3.2a channels, inhibit, schizophrenia, Potassium Channel, PotassiumChannel, recombinant human Kv3 channels
Field of Research
Pharmacology & Drug Discovery
Purity
99.43% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (14.65 mM) ; DMSO:250 mg/mL (732.36 mM)
Smiles
CC[C@H]1NC (=O) N (C1=O) c1ccc (Oc2ccc (C) c (OC) c2) nc1
Molecular Formula
C18H19N3O4
Molecular Weight
341.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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