ERK5-IN-1
ERK5-IN-1 is a potent, dual-activity small molecule inhibitor, demonstrating high potency against ERK5 (IC50 = 87 nM) and the LRRK2[G2019S] mutant (IC50 = 26 nM) . This compound is a valuable chemical probe for investigating the roles of these kinases in cancer and neurodegenerative disease research, both in cellular and biochemical studies.
Product Specifications
CAS Number
1234479-76-5
Product Name Alternative
Inhibit, Extracellular signal regulated kinases, ERK, ERK5 IN 1, ERK5, ERK5IN1, ERK-5-IN-1, ERK5-IN-1, Inhibitor
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
97.70% (May vary between batches)
Solubility
DMSO:25 mg/mL (54.4 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.35 mM)
Smiles
COc1cc (ccc1Nc1ncc2N (C) C (=O) c3ccccc3N (C) c2n1) N1CCN (C) CC1
Molecular Formula
C25H29N7O2
Molecular Weight
459.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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