GC376
GC376 is a potent small molecule inhibitor of 3C-like proteases (3CLpro), exhibiting inhibitory activity in the low micromolar range (IC50 0.49-4.35 μM) . It is widely used in biochemical and cellular assays to study coronavirus replication and has demonstrated antiviral efficacy in feline infectious peritonitis models.
Product Specifications
CAS Number
1416992-39-6
Product Name Alternative
3CLpro, GC376 sodium, GC-376 sodium, SARSCoV
Field of Research
Infectious Disease & Virology
Purity
>95%
Form
Powder
Solubility
DMSO:45 mg/mL (88.66 mM) ;5% DMSO+95% Saline:2.25 mg/mL (4.43 mM)
Smiles
[Na+].[H][C@@] (CC1CCNC1=O) (NC (=O) [C@H] (CC (C) C) NC (=O) OCc1ccccc1) C (O) S ([O-]) (=O) =O
Molecular Formula
C21H30N3NaO8S
Molecular Weight
507.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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