Danirixin
Danirixin (GSK1325756) is a selective and potent CXCR2 antagonist, inhibiting IL-8 binding with an IC50 of 12.5 nM. This small molecule is a valuable research tool for investigating the role of CXCR2 in neutrophil-mediated inflammation in both in vitro and in vivo models.
Product Specifications
CAS Number
954126-98-8
Product Name Alternative
Danirixin, CXC chemokine receptors, CXCR, CXCR2, Inhibitor, GSK 1325756, GSK1325756, GSK-1325756, inhibit
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
DMSO:60 mg/mL (135.78 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (11.31 mM)
Smiles
Cc1c (F) cccc1NC (=O) Nc1ccc (Cl) c (c1O) S (=O) (=O) [C@H]1CCCNC1
Molecular Formula
C19H21ClFN3O4S
Molecular Weight
441.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
