SPHINX31
SPHINX31 is a highly potent and selective SRPK1 inhibitor with an IC50 of 5.9 nM. This compound is a valuable chemical probe for studying SRPK1 function in angiogenesis and splicing regulation in both cellular and animal models of cancer and ocular disease.
Product Specifications
CAS Number
1818389-84-2
Product Name Alternative
Inhibitor, eye disease, HuCCA-1, neovascular, inhibit, Norway Brown rats, diabetics, angiogenic, SPHINX 31, SPHINX31, SPHINX-31, SRPK, SRPK1, retinal permeability, Serine kinase, threoninkinase, threonin kinase, Serinekinase, Serine-arginine protein kinases, VEGFR, Vascular endothelial growth factor receptor
Field of Research
Cardiovascular Research, Cell Biology, Metabolism Research, Signal Transduction
Purity
98.81% (May vary between batches)
Solubility
Ethanol:10 mg/mL (19.7 mM) ; H2O:Insoluble; DMSO:18.85 mg/mL (37.14 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.97 mM)
Smiles
FC (F) (F) c1ccc (N2CCN (Cc3ccccn3) CC2) c (NC (=O) c2ccc (o2) -c2ccncc2) c1
Molecular Formula
C27H24F3N5O2
Molecular Weight
507.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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