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Alrestatin

Alrestatin (AY-22284) is a selective aldose reductase inhibitor. It has been shown in vitro to reduce glucose-stimulated angiotensin II synthesis in rat vascular smooth muscle cells. This compound is a research tool for studying diabetic complications, including nephropathy and retinopathy, in experimental models.

Product Specifications

CAS Number

51411-04-2

Product Name Alternative

Inhibitor, inhibit, Alrestatin, AY22284, AY-22284, AY 22284, Aldose reductase, Aldose Reductase

Field of Research

Metabolism Research

Purity

99.23% (May vary between batches)

Solubility

H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.84 mM) ; DMSO:25 mg/mL (97.95 mM)

Smiles

OC (=O) CN1C (=O) c2cccc3cccc (C1=O) c23

Molecular Formula

C14H9NO4

Molecular Weight

255.2256

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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