BIBF0775
BIBF0775 is a potent and selective inhibitor of the TGFβ type I receptor (ALK5), exhibiting an IC50 of 34 nM. This small molecule is a valuable research tool for studying TGF-β signaling in fibrosis, cancer, and other pathologies, with utility in both cellular and animal models.
Product Specifications
CAS Number
334951-90-5
Product Name Alternative
BIBF 0775, BIBF0775, BIBF-0775, Alk5, inhibit, Inhibitor, Smad, Transforming growth factor beta receptors, TGF-b/Smad, TGFb, TGFbeta, TGFβR1 (ALK5), TGF-β/Smad, TGF-β Receptor, TGFβ, TGFbeta/Smad, TGF-beta
Field of Research
Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.02% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.04 mM) ; DMSO:11 mg/mL (22.24 mM)
Smiles
CCN (C) C (=O) c1ccc2\C (=C (\Nc3ccc (CN4CCCCC4) cc3) c3ccccc3) C (=O) Nc2c1
Molecular Formula
C31H34N4O2
Molecular Weight
494.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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