Indirubin-3'-monoxime
Indirubin-3'-monoxime is a potent, cell-permeable small molecule inhibitor of GSK3β (IC50: 22 nM) and several cyclin-dependent kinases (CDKs) . It is widely used in biochemical and cellular research to study Wnt/β-catenin signaling, cell cycle progression, and neuronal differentiation in both in vitro and in vivo models.
Product Specifications
CAS Number
160807-49-8
Product Name Alternative
Indirubin-3’oxime
Field of Research
Cardiovascular Research, Cell Biology, Neuroscience, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
GSK-3b and CDK inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 6 mg/ml) or in Ethanol (up to 4 mg/ml) .
Smiles
ON=C1C (Nc2ccccc12) =C1C (=O) Nc2ccccc12
Molecular Formula
C16H11N3O2
Molecular Weight
277.29
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-[1,3-Dihydro-3- (hydroxyimino-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one
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