BAI1
BAI1 is a potent small molecule Bax channel blocker that inhibits Bax-induced cytochrome c release from mitochondria with an IC50 of 0.52 μM. It is a valuable research tool for studying apoptosis mechanisms in cellular models and has been used in vitro to investigate cardioprotection and neuroprotection.
Product Specifications
CAS Number
335165-68-9
Product Name Alternative
Pathway, mitochondrial, Inhibitor, inhibit, effector, death, Apoptosis, BAX, Bax, BAI 1, BAI1, BAI-1, Bcl-2 Family, cell, critical
Field of Research
Cell Biology, Signal Transduction
Purity
97.74% (May vary between batches)
Solubility
H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.14 mM) ; DMSO:9.52 mg/mL (20.38 mM)
Smiles
OC (CN1CCNCC1) Cn1c2ccc (Br) cc2c2cc (Br) ccc12
Molecular Formula
C19H21Br2N3O
Molecular Weight
467.2
Storage Conditions
-20°C
Notes
For research use only.
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