NSC 185058
NSC 185058 is a small molecule inhibitor that selectively targets the ATG4B cysteine protease, a key regulator of autophagy. By inhibiting ATG4B, it effectively attenuates autophagic flux and serves as a valuable research tool for studying autophagy in both cellular and animal models of cancer and neurodegenerative diseases.
Product Specifications
CAS Number
39122-38-8
Product Name Alternative
CysteineProtease, Cysteine Protease, Autophagy-related 4, Autophagy, ATG4B, Atg4, Cathepsin, NSC 185058, NSC185058, NSC-185058, Inhibitor, inhibit
Field of Research
Cell Biology, Neuroscience, Protein Biochemistry
Purity
99.27% (May vary between batches)
Solubility
Ethanol:2.5 mg/mL (11.61 mM) ; DMSO:30 mg/mL (139.36 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.29 mM)
Smiles
S=C (Nc1ccccn1) c1ccccn1
Molecular Formula
C11H9N3S
Molecular Weight
215.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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