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3-Methyl-2-oxobutanoic acid

3-Methyl-2-oxobutanoic acid (2-Oxoisovaleric acid) is a neurotoxic keto-acid metabolite from incomplete branched-chain amino acid catabolism, leading to organic acidemias. It is used in research models of maple syrup urine disease (MSUD) to study metabolic acidosis and neurotoxicity in vitro and in vivo.

Product Specifications

CAS Number

759-05-7

Product Name Alternative

Inhibit, Inhibitor, EndogenousMetabolite, Endogenous Metabolite, 3Methyl2oxobutanoic acid, 3-Methyl-2-oxobutanoic acid, 2-Oxoisovaleric acid, 3 Methyl 2 oxobutanoic acid, alpha-Ketoisovaleric acid, a-Ketoisovaleric acid, α-Ketoisovaleric acid

Field of Research

Metabolism Research

Purity

95.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (17.22 mM) ; H2O:100 mg/mL (861.18 mM) ; DMSO:30 mg/mL (258.35 mM)

Smiles

CC (C) C (=O) C (O) =O

Molecular Formula

C5H8O3

Molecular Weight

116.12

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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