Trimethylamine N-oxide dihydrate
Trimethylamine N-oxide dihydrate (TMANO dihydrate) is a gut microbiota metabolite from dietary choline. It promotes cardiac inflammation and fibrosis via ROS/NLRP3 and TGF-β/Smad2 pathways, making it a valuable compound for modeling cardiac hypertrophy and fibrosis in both in vitro and in vivo research.
Product Specifications
CAS Number
62637-93-8
Product Name Alternative
NOD-like Receptor (NLR), Microbe-dependent, metabolite, inhibit, Inhibitor, myocardial, inflammation, Endogenous Metabolite, EndogenousMetabolite, fibrosis, cardiac, choline, dysfunction, TGF-beta/Smad, TGF-βRI, Transforming growth factor beta, trimethylamine, Trimethylamine N oxide dihydrate, Trimethylamine N-oxide, Trimethylamine Noxide dihydrate, Trimethylamine N-oxide Dihydrate, Trimethylamine N-oxide dihydrate, Smad2, TMANO, TMANO Dihydrate, Reactive Oxygen Species
Field of Research
Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (18 mM) ; DMSO:20 mg/mL (179.95 mM)
Smiles
O.O.C[N+] (C) (C) [O-]
Molecular Formula
C3H13NO3
Molecular Weight
111.14
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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