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Skatole

Skatole (3-Methylindole) is a bacterially derived metabolite that acts as an aryl hydrocarbon receptor (AhR) agonist, activating pathways like p38 MAPK to modulate intestinal epithelial function. It is a valuable research tool for studying host-microbiome interactions, gut barrier integrity, and immune signaling in both in vitro and in vivo models.

Product Specifications

CAS Number

83-34-1

Product Name Alternative

P38 MAPK, p38MAPK, Skatole, Scatole, β-Methylindole, EndogenousMetabolite, Endogenous Metabolite, Fungal, Inhibitor, inhibit, Aryl Hydrocarbon Receptor, ArylHydrocarbonReceptor, Autophagy, Bacterial, b-Methylindole, beta-Methylindole, 3-Methyl-1H-indole, 3-Methylindole, 3-​Methylindole, AhR

Field of Research

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Signal Transduction

Purity

99.74% (May vary between batches)

Solubility

DMSO:50 mg/mL (381.18 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (15.25 mM)

Smiles

CC1=CNC2=CC=CC=C12

Molecular Formula

C9H9N

Molecular Weight

131.17

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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