TR-14035
TR-14035 (MDK-1191) is a potent small molecule dual antagonist targeting α4β7 and α4β1 integrins with IC50 values of 7 nM and 87 nM, respectively. It is a valuable research tool for investigating integrin function in inflammatory and autoimmune diseases, supporting both in vitro and in vivo experimental studies.
Product Specifications
CAS Number
232271-19-1
Product Name Alternative
α4β7 integrin, α4β1 integrin, TR 14035, TR14035, TR-14035, MDK1191, MDK-1191, MDK 1191, Inhibitor, Integrin, inhibit, inflammation, disease, alpha (4), asthma, autoimmune, allergic
Field of Research
Signal Transduction
Purity
98.98% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.22 mM) ; DMSO:40 mg/mL (84.33 mM) ; H2O:Insoluble
Smiles
COc1cccc (OC) c1-c1ccc (C[C@H] (NC (=O) c2c (Cl) cccc2Cl) C (O) =O) cc1
Molecular Formula
C24H21Cl2NO5
Molecular Weight
474.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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