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Sobetirome

Sobetirome (IACS-010759) is a selective thyroid hormone receptor beta (TRβ) agonist with an EC50 of 0.16 μM for TRβ-1. This compound is a research tool used in vitro and in vivo to study TRβ-mediated pathways in metabolism, lipid regulation, and related diseases.

Product Specifications

CAS Number

211110-63-3

Product Name Alternative

GC 1, GC1, GC-1, IACS 010759, IACS010759, IACS-010759, inhibit, Inhibitor, Sobetirome, TRβ, THR, QRX 431, QRX431, QRX-431, Thyroidhormonereceptor (THR), Thyroidhormonereceptor, Thyroid Hormone Receptor, Thyroid hormone receptor, Thyroid hormone receptor (THR)

Field of Research

Metabolism Research

Purity

98.08% (May vary between batches)

Solubility

Ethanol:30 mg/mL (91.35 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.09 mM) ; DMSO:145 mg/mL (441.53 mM)

Smiles

CC (C) c1cc (Cc2c (C) cc (OCC (O) =O) cc2C) ccc1O

Molecular Formula

C20H24O4

Molecular Weight

328.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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