Sobetirome
Sobetirome (IACS-010759) is a selective thyroid hormone receptor beta (TRβ) agonist with an EC50 of 0.16 μM for TRβ-1. This compound is a research tool used in vitro and in vivo to study TRβ-mediated pathways in metabolism, lipid regulation, and related diseases.
Product Specifications
CAS Number
211110-63-3
Product Name Alternative
GC 1, GC1, GC-1, IACS 010759, IACS010759, IACS-010759, inhibit, Inhibitor, Sobetirome, TRβ, THR, QRX 431, QRX431, QRX-431, Thyroidhormonereceptor (THR), Thyroidhormonereceptor, Thyroid Hormone Receptor, Thyroid hormone receptor, Thyroid hormone receptor (THR)
Field of Research
Metabolism Research
Purity
98.08% (May vary between batches)
Solubility
Ethanol:30 mg/mL (91.35 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.09 mM) ; DMSO:145 mg/mL (441.53 mM)
Smiles
CC (C) c1cc (Cc2c (C) cc (OCC (O) =O) cc2C) ccc1O
Molecular Formula
C20H24O4
Molecular Weight
328.4
Storage Conditions
-20°C
Notes
For research use only.
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