Trandolapril
Trandolapril is an oral ACE inhibitor prodrug that is metabolized to its active form, trandolaprilat. It is widely used in cardiovascular research, including in vitro enzyme inhibition assays and in vivo models for studying hypertension and heart failure.
Product Specifications
CAS Number
87679-37-6
Product Name Alternative
Congestive heart failure, cellular fibronectin accumulation, collagen, CHF, ACE, arterial hypertrophy, Angiotensin-converting Enzyme, Angiotensin-converting Enzyme (ACE), Angiotensinconverting Enzyme (ACE), AngiotensinconvertingEnzyme, AngiotensinconvertingEnzyme (ACE), hypertension, Inhibitor, nonsulfhydryl, inhibit, myocardial infarction, orally active, spontaneously hypertensive rats, RU 44570, RU44570, RU-44570, UUD model, UUO model, unilateral ureteral obstruction, Trandolaprilat, Trandolapril
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.19% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.29 mM) ; DMSO:100 mg/mL (232.27 mM)
Smiles
C ([C@@H] (N[C@@H] (CCC1=CC=CC=C1) C (OCC) =O) C) (=O) N2[C@@]3 ([C@@] (C[C@H]2C (O) =O) (CCCC3) [H]) [H]
Molecular Formula
C24H34N2O5
Molecular Weight
430.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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