Fluralaner
Fluralaner (A1443) is a potent isoxazoline-class ectoparasiticide that acts by selectively inhibiting insect GABA-gated chloride channels, demonstrated by its high-affinity displacement of EBOB in housefly head membrane assays (IC50 = 455 pM) . It is widely used in veterinary parasitology research for studying ectoparasite control and has applications in both in vitro receptor binding studies and in vivo efficacy models against ticks and fleas.
Product Specifications
CAS Number
864731-61-3
Product Name Alternative
Parasite, inhibit, Fluralaner, GABAReceptor, GABA Receptor, GABA, Inhibitor, AH252723, AH-252723, AH 252723, A1443, A-1443, A 1443
Field of Research
Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery
Purity
99.72% (May vary between batches)
Solubility
H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.19 mM) ; DMSO:100 mg/mL (179.76 mM)
Smiles
Cc1cc (ccc1C (=O) NCC (=O) NCC (F) (F) F) C1=NOC (C1) (c1cc (Cl) cc (Cl) c1) C (F) (F) F
Molecular Formula
C22H17Cl2F6N3O3
Molecular Weight
556.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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