VL285
VL285 is a potent and selective small molecule that recruits the VHL E3 ligase to induce the degradation of HaloTag7 fusion proteins. This PROTAC-based technology enables targeted protein knockdown for functional studies in both cellular and animal models, facilitating research in chemical biology and targeted protein degradation.
Product Specifications
CAS Number
1448188-57-5
Product Name Alternative
Inhibit, Ligands for E3 Ligase, Ligand for E3 Ligase, LigandforE3Ligase, Inhibitor, E3 ligase-recruiting Moiety, VHL, VL 285, VL285, VL-285
Field of Research
Pharmacology & Drug Discovery
Purity
99.85% (May vary between batches)
Solubility
DMSO:53.26 mg/mL (99.99 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.75 mM)
Smiles
[C@@H] (C (=O) N1[C@H] (C (NCC2=CC=C (C=C2) C3=C (C) N=CS3) =O) C[C@@H] (O) C1) ([C@H] (C) C) N4C (=O) C=5C (C4) =CC=CC5
Molecular Formula
C29H32N4O4S
Molecular Weight
532.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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