WYC-209
WYC-209 is a retinoic acid receptor (RAR) -targeting small molecule that potently suppresses the proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with an IC50 of 0.19 μM. This inhibitor is a useful research tool for studying RAR signaling in cancer stemness and tumorigenesis in both in vitro and in vivo models.
Product Specifications
CAS Number
2131803-90-0
Product Name Alternative
Autophagy, Apoptosis, Inhibitor, inhibit, Retinoic acid receptors, RetinoidReceptor, Retinoid X receptors, Retinoid Receptor, RAR/RXR, RAR, WYC 209, WYC209, WYC-209
Field of Research
Cell Biology, Metabolism Research
Purity
98.91% (May vary between batches)
Solubility
H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.96 mM) ; DMSO:80 mg/mL (217.13 mM)
Smiles
CCOC (=O) c1cnc (nc1) C#Cc1ccc2c (c1) C (C) (C) CCS2=O
Molecular Formula
C20H20N2O3S
Molecular Weight
368.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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