IWP-O1
IWP-O1 is a potent small molecule Porcn inhibitor with an EC50 of 80 pM. It effectively blocks Wnt signaling by inhibiting Dvl2/3 and LRP6 phosphorylation in vitro, making it a valuable tool for studying Wnt pathway biology in cancer and developmental research.
Product Specifications
CAS Number
2074607-48-8
Product Name Alternative
Beta-catenin, betacatenin, bcatenin, Inhibitor, inhibit, IWP O1, IWPO1, IWP-O1, IWP-O-1, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, Wnt, Porcupine, Porcn, βcatenin
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
99.12% (May vary between batches)
Solubility
DMSO:60 mg/mL (138.73 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.62 mM)
Smiles
O=C (Cn1nnc (c1-c1ccccc1) -c1ccncc1) Nc1ccc (cn1) -c1ccccc1
Molecular Formula
C26H20N6O
Molecular Weight
432.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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