S63845
S63845 is a potent and selective small molecule inhibitor of myeloid cell leukemia 1 (MCL1), exhibiting high-affinity binding with a Kd of 0.19 nM. It is a valuable research tool for studying MCL1-dependent apoptosis in cancer models, including in vitro cell-based assays and in vivo studies of hematological malignancies.
Product Specifications
CAS Number
1799633-27-4
Product Name Alternative
Bcl-2 Family, Inhibitor, inhibit, MCL-1, S63845, S-63845, S 63845
Field of Research
Cell Biology
Purity
97.70% (May vary between batches)
Solubility
DMSO:33.33 mg/mL (40.19 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.41 mM)
Smiles
O=C (O) C (OC1=NC=NC=2SC (C=3OC (F) =CC3) =C (C=4C=CC (OCCN5CCN (C) CC5) =C (Cl) C4C) C12) CC=6C=CC=CC6OCC7=CC=NN7CC (F) (F) F
Molecular Formula
C39H37ClF4N6O6S
Molecular Weight
829.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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