ABX-1431
ABX-1431 (Elcubragistat) is a potent, brain-penetrant, and orally bioavailable small molecule inhibitor of monoacylglycerol lipase (MGLL) with an IC50 of 14 nM. It is a valuable research tool for investigating endocannabinoid signaling in preclinical models of neurological disorders, including neuroinflammation and pain.
Product Specifications
CAS Number
1446817-84-0
Product Name Alternative
MAGL, Inhibitor, Elcubragistat, inhibit, Monoacylglycerol lipase, ABX1431, ABX-1431, ABX 1431
Field of Research
Metabolism Research
Purity
99.27% (May vary between batches)
Solubility
H2O:Insoluble; Ethanol:10 mg/mL (19.71 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (4.93 mM) ; DMSO:55 mg/mL (108.4 mM)
Smiles
FC (F) (F) C (OC (=O) N1CCN (Cc2ccc (cc2N2CCCC2) C (F) (F) F) CC1) C (F) (F) F
Molecular Formula
C20H22F9N3O2
Molecular Weight
507.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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