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IRAK4-IN-7

IRAK4-IN-7 (CA-4948) is a potent and selective inhibitor of IRAK4 kinase. It demonstrates in vivo efficacy by reducing cytokine release in TLR4-driven models, supporting its use in research on autoimmune diseases and hematologic cancers.

Product Specifications

CAS Number

1801343-74-7

Product Name Alternative

Lymphoma, IRAK4IN7, IRAK-4-IN-7, IRAK4-IN-7, IRAK4 IN 7, IRAK-4, IRAK4, IRAK, Interleukin-1 receptor associated kinase, IL-1R associated kinase, inhibit, non-Hodgkin, Inhibitor, large B cell lymphoma, diffuse, DLBCL, CA 4948, CA4948, CA-4948, ABC-type

Field of Research

Immunology & Inflammation, Signal Transduction

Purity

99.50% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.4 mM) ; DMSO:13.89 mg/mL (33.28 mM)

Smiles

Nc1ccc (cn1) -c1cccc (n1) C (=O) Nc1cnc2nc (oc2c1) N1CCOCC1

Molecular Formula

C21H19N7O3

Molecular Weight

417.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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