IRAK4-IN-7
IRAK4-IN-7 (CA-4948) is a potent and selective inhibitor of IRAK4 kinase. It demonstrates in vivo efficacy by reducing cytokine release in TLR4-driven models, supporting its use in research on autoimmune diseases and hematologic cancers.
Product Specifications
CAS Number
1801343-74-7
Product Name Alternative
Lymphoma, IRAK4IN7, IRAK-4-IN-7, IRAK4-IN-7, IRAK4 IN 7, IRAK-4, IRAK4, IRAK, Interleukin-1 receptor associated kinase, IL-1R associated kinase, inhibit, non-Hodgkin, Inhibitor, large B cell lymphoma, diffuse, DLBCL, CA 4948, CA4948, CA-4948, ABC-type
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
99.50% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.4 mM) ; DMSO:13.89 mg/mL (33.28 mM)
Smiles
Nc1ccc (cn1) -c1cccc (n1) C (=O) Nc1cnc2nc (oc2c1) N1CCOCC1
Molecular Formula
C21H19N7O3
Molecular Weight
417.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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