MRT68921 HCl
MRT68921 hydrochloride is a highly potent dual inhibitor of the autophagy-initiating kinases ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. This compound is a valuable research tool for investigating autophagy mechanisms in both cellular and animal models of cancer and neurodegenerative diseases.
Product Specifications
CAS Number
2070014-87-6
Product Name Alternative
MRT68921 HCl, MRT-68921 HCl, ULK1, ULK2
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.15% (May vary between batches)
Solubility
DMSO:4.72 mg/mL (10.02 mM) ; H2O:10 mg/mL (21.23 mM)
Smiles
Cl.CN1CCc2cc (Nc3ncc (C4CC4) c (NCCCNC (=O) C4CCC4) n3) ccc2C1
Molecular Formula
C25H34N6O·HCl
Molecular Weight
471.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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