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MRT68921 HCl

MRT68921 hydrochloride is a highly potent dual inhibitor of the autophagy-initiating kinases ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. This compound is a valuable research tool for investigating autophagy mechanisms in both cellular and animal models of cancer and neurodegenerative diseases.

Product Specifications

CAS Number

2070014-87-6

Product Name Alternative

MRT68921 HCl, MRT-68921 HCl, ULK1, ULK2

Field of Research

Cell Biology, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.15% (May vary between batches)

Solubility

DMSO:4.72 mg/mL (10.02 mM) ; H2O:10 mg/mL (21.23 mM)

Smiles

Cl.CN1CCc2cc (Nc3ncc (C4CC4) c (NCCCNC (=O) C4CCC4) n3) ccc2C1

Molecular Formula

C25H34N6O·HCl

Molecular Weight

471.04

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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