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Loreclezole

Loreclezole is a selective positive allosteric modulator of GABAA receptors containing β2 or β3 subunits. It is a valuable research tool for studying GABAergic neurotransmission in neurological and psychiatric disorders, utilized in both in vitro binding assays and in vivo models of epilepsy and anxiety.

Product Specifications

CAS Number

117857-45-1

Product Name Alternative

GABA Receptor, GABAA, GABAReceptor, Gamma-aminobutyric acid Receptor, Inhibitor, inhibit, Loreclezole, R 72063, R72063, R-72063, γ-Aminobutyric acid Receptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.78% (May vary between batches)

Solubility

DMSO:90 mg/mL (327.83 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.02 mM)

Smiles

Cl\C (=C/n1cncn1) c1ccc (Cl) cc1Cl

Molecular Formula

C10H6Cl3N3

Molecular Weight

274.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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