Loreclezole
Loreclezole is a selective positive allosteric modulator of GABAA receptors containing β2 or β3 subunits. It is a valuable research tool for studying GABAergic neurotransmission in neurological and psychiatric disorders, utilized in both in vitro binding assays and in vivo models of epilepsy and anxiety.
Product Specifications
CAS Number
117857-45-1
Product Name Alternative
GABA Receptor, GABAA, GABAReceptor, Gamma-aminobutyric acid Receptor, Inhibitor, inhibit, Loreclezole, R 72063, R72063, R-72063, γ-Aminobutyric acid Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.78% (May vary between batches)
Solubility
DMSO:90 mg/mL (327.83 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.02 mM)
Smiles
Cl\C (=C/n1cncn1) c1ccc (Cl) cc1Cl
Molecular Formula
C10H6Cl3N3
Molecular Weight
274.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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