D3-βArr
D3-βArr (NCGC00379308) is a small molecule positive allosteric modulator of the thyrotropin receptor (TSHR) . Its direct activation of TSHR induces β-arrestin 1 translocation with an EC50 of 11.6 μM, making it a useful research tool for studying TSHR signaling and related GPCR pathways in cellular models.
Product Specifications
CAS Number
662164-09-2
Product Name Alternative
D3 βArr, D3-bArr, D3-betaArr, D3βArr, D-3-βArr, D3-βArr, Inhibitor, inhibit, NCGC00379308, NCGC-00379308, NCGC 00379308, Thyrotropin receptor, thyrotropin receptor (TSHR), Thyroid-stimulating hormone Receptor, TSH Receptor, TSHReceptor
Field of Research
Pharmacology & Drug Discovery
Purity
98.82% (May vary between batches)
Solubility
DMSO:100 mg/mL (299.91 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12 mM)
Smiles
CC (Nc1nc (nc2ccccc12) N1CCNCC1) c1ccccc1
Molecular Formula
C20H23N5
Molecular Weight
333.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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