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LP-211

LP-211 is a potent and selective 5-HT7 receptor agonist with high brain penetrance, exhibiting a Ki of 0.58 nM and over 300-fold selectivity versus the 5-HT1A receptor. This tool compound is widely used in neuroscience research to investigate the receptor's role in circadian rhythms, learning, and mood, utilizing both in vitro binding assays and in vivo behavioral models.

Product Specifications

CAS Number

1052147-86-0

Product Name Alternative

5-HT7, 5HT Receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, 5-HT1A, 5-HT Receptor, D2, Dopamine Receptor, DopamineReceptor, inhibit, Inhibitor, LP 211, LP211, LP-211, Serotonin Receptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.65% (May vary between batches)

Solubility

DMSO:90 mg/mL (192.88 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.07 mM)

Smiles

C (CCCCC (NCC1=CC=C (C#N) C=C1) =O) N2CCN (C3=C (C=CC=C3) C4=CC=CC=C4) CC2

Molecular Formula

C30H34N4O

Molecular Weight

466.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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