LP-211
LP-211 is a potent and selective 5-HT7 receptor agonist with high brain penetrance, exhibiting a Ki of 0.58 nM and over 300-fold selectivity versus the 5-HT1A receptor. This tool compound is widely used in neuroscience research to investigate the receptor's role in circadian rhythms, learning, and mood, utilizing both in vitro binding assays and in vivo behavioral models.
Product Specifications
CAS Number
1052147-86-0
Product Name Alternative
5-HT7, 5HT Receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, 5-HT1A, 5-HT Receptor, D2, Dopamine Receptor, DopamineReceptor, inhibit, Inhibitor, LP 211, LP211, LP-211, Serotonin Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.65% (May vary between batches)
Solubility
DMSO:90 mg/mL (192.88 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.07 mM)
Smiles
C (CCCCC (NCC1=CC=C (C#N) C=C1) =O) N2CCN (C3=C (C=CC=C3) C4=CC=CC=C4) CC2
Molecular Formula
C30H34N4O
Molecular Weight
466.62
Storage Conditions
-20°C
Notes
For research use only.
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