CK1-IN-1
CK1-IN-1 (PUN51207) is a potent and selective small molecule inhibitor of casein kinase 1, demonstrating IC50 values of 15 nM for CK1δ, 16 nM for CK1ε, and 73 nM for p38σ MAPK. This compound is a valuable research tool for studying CK1 signaling in circadian rhythms, Wnt/β-catenin pathways, and neurodegenerative disease models, both in vitro and in vivo.
Product Specifications
CAS Number
1784751-20-7
Product Name Alternative
CK1, CK1 IN 1, CK1IN1, CK-1-IN-1, CK1-IN-1, Casein Kinase, CaseinKinase, inhibit, Inhibitor, PUN 51207, PUN51207, PUN-51207, p38σ MAPK, p38MAPK, p38 MAPK
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.79% (May vary between batches)
Solubility
DMSO:60 mg/mL (156.5 mM) ; H2O:Insoluble
Smiles
Fc1ccc (cc1) -c1nc ([nH]c1-c1ccncc1) -c1ccc2ccccc2c1F
Molecular Formula
C24H15F2N3
Molecular Weight
383.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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