GeA-69
GeA-69 is a selective, allosteric inhibitor targeting the PARP14 macrodomain 2 (MD2), with a binding affinity (Kd) of 0.86 μM. This small molecule is a valuable research tool for investigating PARP14's role in cancer, inflammation, and viral infection through in vitro biochemical and cellular studies.
Product Specifications
CAS Number
2143475-98-1
Product Name Alternative
Cytotoxicity, DNA damage repair mechanism, cell permeable, HeLa, HEK293, intact cell, Inhibitor, GeA 69, GeA69, GeA-69, inhibit, poly ADP ribose polymerase, PARP, PARP14, U-2 OS
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
99.75% (May vary between batches)
Solubility
DMSO:120 mg/mL (399.53 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.32 mM)
Smiles
CC (=O) Nc1ccccc1-c1cccc2c3ccccc3[nH]c12
Molecular Formula
C20H16N2O
Molecular Weight
300.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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