Q203
Telacebec (Q203) is a potent small-molecule inhibitor targeting the cytochrome b subunit QcrB of Mycobacterium tuberculosis, exhibiting potent activity with an MIC50 of 2.7 nM against the H37Rv strain. It serves as a key research tool for investigating mycobacterial respiration and has demonstrated efficacy in both in vitro assays and in vivo mouse models of tuberculosis infection.
Product Specifications
CAS Number
1334719-95-7
Product Name Alternative
Bacterial, Antibiotic, IAP 6, IAP6, IAP-6, Inhibitor, inhibit, Q 203, Q203, Q-203, tuberculosis, Telacebec
Field of Research
Infectious Disease & Virology
Purity
98.02% (May vary between batches)
Solubility
H2O:Insoluble; DMSO:11 mg/mL (19.75 mM)
Smiles
CCc1nc2ccc (Cl) cn2c1C (=O) NCc1ccc (cc1) N1CCC (CC1) c1ccc (OC (F) (F) F) cc1
Molecular Formula
C29H28ClF3N4O2
Molecular Weight
557.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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