BI-1347
BI-1347 is a highly potent and selective CDK8/cyclin C kinase inhibitor with an IC50 of 1 nM. It has demonstrated efficacy in suppressing tumor growth in xenograft models, supporting its use in oncology research for studying transcriptional regulation and cancer cell proliferation in both cellular and animal studies.
Product Specifications
CAS Number
2163056-91-3
Product Name Alternative
Cyclin dependent kinase, CDK8, CDK, BI 1347, BI1347, BI-1347, anti-tumoral activity, inhibit, mouse splenic NK cell, oral activity, Inhibitor, human NK92MI cell, selectivity
Field of Research
Cell Biology
Purity
96.70% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.22 mM) ; DMSO:120 mg/mL (336.68 mM)
Smiles
CN (C) C (=O) Cn1cc (cn1) -c1ccc (cc1) -c1cncc2ccccc12
Molecular Formula
C22H20N4O
Molecular Weight
356.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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