Branebrutinib
Branebrutinib (BMS-986195) is a highly selective, covalent Bruton's tyrosine kinase (BTK) inhibitor with sub-nanomolar potency. Its >5,000-fold selectivity over kinases outside the Tec family makes it a valuable tool for investigating BTK-dependent signaling in autoimmune and oncology research, applicable in both cellular and animal models.
Product Specifications
CAS Number
1912445-55-6
Product Name Alternative
BTK, Btk, BMS 986195, BMS986195, BMS-986195, Branebrutinib, Bruton tyrosine kinase, inhibit, Inhibitor
Field of Research
Cardiovascular Research, Signal Transduction
Purity
95.02% (May vary between batches)
Solubility
DMSO:100 mg/mL (269.96 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.91 mM)
Smiles
CC#CC (=O) N[C@H]1CCCN (C1) c1c (F) cc (C (N) =O) c2[nH]c (C) c (C) c12
Molecular Formula
C20H23FN4O2
Molecular Weight
370.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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